Our TTC Timeline

5/2007 Stopped Depo Shot/No further birth control use – Not preventing, but not trying really

4/2008 Married my soul mate. ♥ Not trying, not preventing *but hoping* for 1 year

4/2009 Actively began TTC with OPKs and timed intercourse

9/2009 Joined TwoWeekWait.com and began charting on fertilityfriend.com

4/2009 through 12/2009 – 10 cycles TTC Naturally, some cycles with Soy or other supplements and TTC aids: 8 BFNs and 2 early losses 6/09 and 8/09 – Confirmed with betas

12/2009
First RE consult
-HSG all clear and S/A normal
-Recurrent pregnancy loss testing all normal (He didn’t test for much.)
-Blood work revealed High FSH & Low AMH
-First Dx: Diminished Ovarian Reserve/High FSH/Poor ovarian function at age 27

1/2010 Cycle 11 – Clomid trial and timed intercourse: BFN

2/2010 Cycle 12 – IUI #1 w/ Clomid, hcg trigger, and progesterone: BFN

3/2010 Cycle 13 – IUI #2 w/ Clomid, hcg trigger, and progesterone: BFN

4/2010 Began blogging

4/2010 Cycle 14 – IUI #3 w/ Clomid, hcg trigger, and progesterone: BFP – early loss 4/10 (Confirmed with beta)

5/2010 Cycle 15 – IUI #4 w/ Follistim, Estrogen, hcg trigger, progesterone, and hcg booster shot: BFN

6/15/10 IVF Consult – Cycle on hold until October 2010

6/2010 Cycles 16 & 17 – TTC Naturally: BFNs

7/2010 Cycle 18 – Clomid, Follistim, hcg trigger shot, progesterone, and timed intercourse: BFN

8/2010 Cycle 19 – TTC Naturally: BFN

9/2010 Cycle 20 – TTC Naturally: BFN

10/2010 Cycle 21 – IVF #1 (Poor response – Converted to IUI #5) – Lupron flare, Gonal F, hcg trigger, progesterone, and hcg booster shot: BFP – early loss 11/10 (Confirmed with beta)

10/2010 – 2 second opinions. Chose RE #2 and set up new plan/new protocol for IVF #2 in January 2011

11/2010 Cycle 22 – TTC Naturally: BFN

12/2010 Cycle 23 – TTC Naturally: BFN

12/2010 New Dx: Premature Ovarian Failure ???

1/2011 Cycle 24 – IVF #2! With ICSI, Assisted Hatching, Antagonist protocol, and new RE! BFP – early loss 2/11 (Beta #1: 6, Beta #2: 2)

2/2011
-Completed more RPL loss testing –
-DX: Elevated Antiphosphatidylserine IGM!
-(Blood clotting disorder in the autoimmune category – treat with Lovenox)

2/2011 Cycle 25 – TTC naturally: BFN

3/2011 Cycle 26 – TTC Naturally (with Lovenox during TWW): BFP – early loss 3/11 (Confirmed with beta)

4/2011 Cycle 27 – (IUI #6 had to be canceled due to dominant follie ready to O on CD 9) Femara 5mg CD 3-7, Follistim 150 units CD 5-trigger, Ovidrel trigger, Dexamethasone 4mg, Lovenox 40 units, progesterone, and timed intercourse: BFN (but with some questionable negative and positive HPTs)

5/2011 Cycle 28 – Clomid 100mg CD 2-6, Ovidrel trigger, Dexamethasone 4mg, Lovenox 40 units, progesterone, and timed intercourse: BFN

6/2011 Cycle 29 – TTC Naturally: BFN

6/2011
Consult with Dr. Sher of SIRM
-Suspected Immunologic Implantation Dysfunction
-Full panel of autoimmune/RPL testing – 21 tests

6/2011 – 7/2011 Cycle 30 – TTC Naturally: BFN

7/2011 Cycle 31 – Clomid 100mg CD 3-7, Menopur 150iu CD 5-trigger, Ovidrel trigger, Dexamethasone 4mg, Lovenox 40 units, progesterone, and timed intercourse: BFP – early loss 8/11 (Confirmed with beta)

8/2011 Results in from Dr. Sher. He explained to us that we will most likely need a surrogate to have a baby. 😦 Labs revealed more new Dxs – Activated Natural Kills Cells, Complete Alloimmune Implantation Dysfunction, and DQ Alpha/HLA match. Click here for appt post. Cycles 32 & 33 – NT/NP: BFNs

9/2011 – 10/2011 Cycle 34 – Last refill of Clomid 100mg CD 3-7 and Dexamethasone. Fingers crossed for a miracle. BFP!!! – After the most promising betas ever, we miscarried at 5 weeks, 2 days. 😦

10/2011 – 11/2011 Cycle 35 – NT/NP: BFN

11.22.11 Lap/HSG/D&C – New Dxs – Stage II Endometriosis throughout uterus, film/scar tissue over right ovary, congenital Septate Uterus: All removed/repaired! Possibly the true reason for multiple miscarriages and chemical pregnancies! Click here for surgery post.

11/2011 – 1/2012 Taking Estrace tablets 2x day for 45 days to rebuild my lining, followed by Provera for 10 days to re-boot my body and start a fresh cycle

12/2011 EEK! I actually ovulated right on schedule after surgery! Cycle 36 – TTC Naturally: BFN

12/2011 – 1/2012 Cycle 37 – TTC Naturally: BFN (but with some questionable tests – no beta)

1/2012 – 2/2012 Cycle 38 – Femara 5mg CD 3-7, Ovidrel trigger, Dex, progesterone, and timed intercourse: BFN (questionable tests again – beta was 3)

2/2012 – 3/2012 Cycle 39 – Femara 5mg CD 3-7, Menopur 150 units CD 5-trigger, Ovidrel trigger, Dex, progesterone, and timed intercourse: BFP for 3-4 days (11-13dpo progressed), then BFN at 15dpo – no beta.

3/1/12 Consult/2nd opinion with Dr. James, RE (AKA Dr. Meany): Recommends donor eggs 😦 However, she will treat for immune issues, so we will pursue that first.

3/2012 Cycle 40 – IUI #6 w/ Estrogen 2mg CD 1-4, Femara 5mg CD 3-7, Menopur 225 units CD 5-trigger, Ovidrel trigger, Dex, progesterone: BFP – promising progression 8dpo-12dpo and first beta was great, but slow dropping betas starting at 14dpo.

4/2012 Cycle 41 – Not really TTC. Whatever happens, happens: BFN

4/23/12 Consult/2nd opinion (in regards to Dr. Sher’s testing) with Dr. Kwak-Kim, Reproductive Immunologist (click here for appt post) Another new Dx of poor blood flow to the uterus.

5/23/12 Follow up and test results via phone conference w/ Dr. Kwak-Kim: More new Dxs revealed – 3 blood clotting disorders, more inflammatory/autoimmune markers, atypical PCOS. Click here for f/u post.

5/2012 Cycle 42 – Estrogen 2mg CD 1-3, Femara 7.5mg (3 tablets) CD 3-7, Menopur 225 units CD 5-trigger, Ovidrel trigger, Dex 8mg everyday, Lovenox 40 units everyday, progesterone, and timed intercourse: BFN

6/2012 Cycle 43 – Metformin 1,000mg everyday, extra Folic Acid/B Vitamins, supplements, Lovenox 40 units from CD 6 on, Prednisone 10mg starting at 2dpo, Prometrium 200mg starting at 2dpo, and timed intercourse: BFP! Bleeding and beta of 8 @ 13dpo. Beta only increased to 13 on 15dpo. Subsequent tests faded quickly and bleeding got much heavier.

7/2012 Cycle 44 – Metformin 1,000mg everyday, extra Folic Acid/B Vitamins, supplements, Lovenox 40 units from CD 6 on, Prednisone 10mg starting at 2dpo, Prometrium 400mg starting at 2dpo, and timed intercourse: BFN

7/30/12 Labs show that the new meds are working! No IVIG needed!

8/2012 Cycle 45 – Femara 5mg CD 3-7, Metformin 1,000mg everyday, prescription strength Folic Acid/B Vitamins, supplements, Lovenox 40 units from CD 6 on, Prednisone 10mg starting at 2dpo, Prometrium 400mg starting at 2dpo, and timed intercourse: BFP! Beta of 5 @ 14dpo. Beta decreased to 4 on 17dpo. Spotting started at 15dpo.

9/2012 Cycle 46 – Began gluten-free diet. New plan from Dr. KK to check betas at 10dpo & every 2 days. Metformin 1,000mg everyday, extra Folic Acid/B Vitamins, supplements, Lovenox 40 units from CD 6 on, Prednisone 10mg starting at 2dpo, Progesterone 400mg starting at 2dpo, and timed intercourse: BFN – tests and betas both. There were a few positives at 9dpo, but nothing prior or after that.

10/2012 Cycle 47 – A cyst on my left ovary 😦 Cycle on hold. Birth control pills. Re-check on 10/22/12. Cyst still there! Continued BCPs until 11/9/12. Cyst gone after 36 days. AF came on CD 39.

10/17/2012 Further allergy testing – inconclusive (probably false negatives) due to steroids for TTC.

11/2012 -12/2012 Cycle 48 – Femara 5mg CD 3-7, Follistim 150 units CD 5-9, Metformin 1,000mg everyday, extra Folic Acid/B Vitamins, supplements, Lovenox 40 units from CD 6 on, Prednisone 10mg starting at 2dpo, Progesterone 400mg starting at 2dpo, and timed intercourse: BFP!! Beta # 1 @ 12dpo = 60, Progesterone @ 12dpo = 19, Estradiol @ 12dpo = 994, Beta # 2 @ 14dpo = 86, Beta # 3 @ 16dpo = 217, Beta # 4 @ 19dpo = 733, Beta # 5 @ 21dpo = 1,614! Continue betas every 2 days for about 6 weeks. First u/s 12/21/12 @ 5 weeks, 2 days – There is 1 perfect baby bean! Saw sac and fetal pole! Due 8.20.13!